Deca Durabolin - Pros and Cons of Nandrolone Decanoate

Deca Durabolin 100mg is the injectable steroid Nandrolone Decanoate. This compound came around early in the wave of commercial steroid development, first being made available as a prescription medication in 1962. Deca Durabolin is one of the most widely used anabolic steroids. Its popularity is due to the simple fact that it exhibits many favorable properties.

Structurally Deca Durabolin 100mg is the injectable steroid Nandrolone Decanoate. This compound came around early in the wave of commercial steroid development, first being made available as a prescription medication in 1962. Deca Durabolin is one of the most widely used anabolic steroids. Its popularity is due to the simple fact that it exhibits many favorable properties.

Structurally Nandrolone Decanoate is very similar to testosterone, although it lacks a carbon atom at the 19th position (hence its other name 19-nortestosterone). The resulting structure is a steroid that exhibits much weaker androgenic properties than testosterone. Of primary interest is the fact that nandrolone will not break down to a more potent metabolite in androgen target tissues.

You may remember this is a significant problem with testosterone. Although Nandrolone Decanoate does undergo reduction via the same (5-alpha reductase) enzyme that produces DHT from testosterone, the result in this case is dihydro nandrolone. This metabolite is weaker than the parent nandrolone, and is far less likely to cause unwanted androgenic side effects.

Deca Durabolin (”Deca”) is actually the brand name for the compound Nandrolone Decanoate. This is a 19-Nor compound (some would say that it is the 19-norcompound), and as such, it shares basically the same characteristics with all of them. One thing unique about Deca Durabolin, above nearly all steroids, is the mystique it has had for the last quarter of a century. Deca cycles at doses ranging from 100mgs/weekto2, 000mgs per week. Deca Durabolin (and Nandrolone in general) doesn’t produce many estrogenic or androgenic side effects.

This is because Deca Durabolin has a very low rate of aromatization (conversion to estrogen via the aromatase enzyme); roughly equal to 20% the rate of Testosterone. Deca Durabolin also has a very long active life. Deca Durabolin produces relatively active and stable plasma Nandrolone Decanoate levels until day almost 10, hence once a week injections are all that’s necessary for stable levels of Nandrolone decanoate (the Nandrolone phenyl propionate used I was active, and only experienced a severe drop off around day 5). You’ll also note that higher blood plasma levels of Nandrolone Decanoate are found with Gluteal injections as opposed to Deltoid injections (this is true for all oil-based steroids).

What Is It?

Nandrolone Decanoate strongly resembles the molecular structure of the hormone testosterone, and produces a number of similar anabolic side effects. Nandrolone Decanoate increase muscle mass, promotes bone density and stimulates appetite. It differs from testosterone by having weak androgenic properties (ability to cause masculine characteristics).

Medical Uses

Nandrolone decanoate received FDA approval in 1983 to treat a number of medical conditions. Doctors have used Nandrolone Decanoate to increase red blood cell counts to treat anaemia of the kidneys. It has also been used to treat post-menopausal osteoporosis and has been prescribed as a contraceptive for women. As an oil-based steroid, patients must inject Nandrolone Decanoate into intra-muscular tissue. Typical dosages range from 50 to 100 mg per week for women and 100 to 200 mg per week for men.

Athletic Uses

Nandrolone Decanoate increases muscle mass by facilitating nitrogen retention in muscle tissues, and consequently many athletes have taken it to aid the recovery after muscle injury. Nandrolone Decanoate also helps recovery from and prevents joint injuries by storing excess water (as synovial fluid) in the joints, and this additional joint lubrication has encouraged Nandrolone use among strength athletes.

Contraindications

Men with pre-existing prostate carcinoma (a form of cancer) or members of either sex with breast carcinoma should not take Nandrolone Decanoate. Also, women with hypocalcaemia (excess calcium in the bones), or women who could become pregnant during use should not take Nandrolone Decanoate.
is very similar to testosterone, although it lacks a carbon atom at the 19th position (hence its other name 19-nortestosterone). The resulting structure is a steroid that exhibits much weaker androgenic properties than testosterone. Of primary interest is the fact that nandrolone will not break down to a more potent metabolite in androgen target tissues.

You may remember this is a significant problem with testosterone. Although Nandrolone Decanoate does undergo reduction via the same (5-alpha reductase) enzyme that produces DHT from testosterone, the result in this case is dihydro nandrolone. This metabolite is weaker than the parent nandrolone, and is far less likely to cause unwanted androgenic side effects.

Deca Durabolin (”Deca”) is actually the brand name for the compound Nandrolone Decanoate. This is a 19-Nor compound (some would say that it is the 19-norcompound), and as such, it shares basically the same characteristics with all of them. One thing unique about Deca Durabolin, above nearly all steroids, is the mystique it has had for the last quarter of a century. Deca cycles at doses ranging from 100mgs/weekto2, 000mgs per week. Deca Durabolin (and Nandrolone in general) doesn’t produce many estrogenic or androgenic side effects.

This is because Deca Durabolin has a very low rate of aromatization (conversion to estrogen via the aromatase enzyme); roughly equal to 20% the rate of Testosterone. Deca Durabolin also has a very long active life. Deca Durabolin produces relatively active and stable plasma Nandrolone Decanoate levels until day almost 10, hence once a week injections are all that’s necessary for stable levels of Nandrolone decanoate (the Nandrolone phenyl propionate used I was active, and only experienced a severe drop off around day 5). You’ll also note that higher blood plasma levels of Nandrolone Decanoate are found with Gluteal injections as opposed to Deltoid injections (this is true for all oil-based steroids).

What Is It?

Nandrolone Decanoate strongly resembles the molecular structure of the hormone testosterone, and produces a number of similar anabolic side effects. Nandrolone Decanoate increase muscle mass, promotes bone density and stimulates appetite. It differs from testosterone by having weak androgenic properties (ability to cause masculine characteristics).

Medical Uses

Nandrolone decanoate received FDA approval in 1983 to treat a number of medical conditions. Doctors have used Nandrolone Decanoate to increase red blood cell counts to treat anaemia of the kidneys. It has also been used to treat post-menopausal osteoporosis and has been prescribed as a contraceptive for women. As an oil-based steroid, patients must inject Nandrolone Decanoate into intra-muscular tissue. Typical dosages range from 50 to 100 mg per week for women and 100 to 200 mg per week for men.

Athletic Uses

Nandrolone Decanoate increases muscle mass by facilitating nitrogen retention in muscle tissues, and consequently many athletes have taken it to aid the recovery after muscle injury. Nandrolone Decanoate also helps recovery from and prevents joint injuries by storing excess water (as synovial fluid) in the joints, and this additional joint lubrication has encouraged Nandrolone use among strength athletes.

Contraindications

Men with pre-existing prostate carcinoma (a form of cancer) or members of either sex with breast carcinoma should not take Nandrolone Decanoate. Also, women with hypocalcaemia (excess calcium in the bones), or women who could become pregnant during use should not take Nandrolone Decanoate.

Deca Durabolin use and side effects

Deca Durabolin or Nandrolone Decanoate is perhaps the second-best known injectable anabolic steroid after Testosterone. This anabolic steroid was originally developed to combat wasting diseases when patients were restricted to bed rest or were unable to exercise to maintain lean mass throughout recovery. Soon, it gained prominence as a drug to build lean muscle mass and improve body strength.

Nandrolone Decanoate is admired by those into athletics and bodybuilding because of its ability to improve muscle growth, appetite stimulation, red blood cell production, and bone density. Use of this potent anabolic steroid is also associated with ‘curing’ joint problems that happen during intense workouts. Deca Durabolin is also used during a cutting cycle to lose body fat and can be taken in both the off-season and before a professional bodybuilding contest. Deca Durabolin is generally used during mass gain and dieting phases. It is considered by many as the safest and the most effective injectable anabolic steroid since it promotes the increase of muscle tissue buildup. Deca Durabolin exhibits a great affinity for the androgen receptor in muscle tissue, binding far more successfully than that of testosterone. This anabolic steroid is also admired for its ability to promote good size and moderate strength gains, with a tendency to reduce body fat stores.

Deca Durabolin use does not negatively affect the immune system in the manner like some derivatives of testosterone and the steroid actually leads to a very positive immune system effect. Moreover, this anabolic steroid does not negatively affect any of the body connective tissues such as elbow and knee joints. This anabolic steroid compound is an instant hit among athletes and bodybuilders because of its anabolic properties, with low androgenic activity. The fears of a bad lipid profile or high levels of bad cholesterol are unfounded with Deca Durabolin, as studies show Deca Durabolin actually improves HDL cholesterol levels.

Deca Durabolin is a well-liked by professional athletes and bodybuilders and some of the most admired sports personalities including Merlene Ottey, Dieter Baumann, Linford Christie, American shotputter C.J. Hunter, five-time gold medalist for track and field Marion Jones, South Africa rugby league footballer Jamie Bloem, Roger Clemens, Barry Bonds, UFC Hall of Famer Royce Gracie, Pakistani cricketer Shoaib Akhtar, and British tennis player Greg Rusedski have admitted to or accused of using Deca Durabolin.

The recommended dose of Deca Durabolin for men is 2mg per pound of body weight or 250–500mg per week though it is even taken by some athletes in low doses at 200mg per week or as high as 400mg per week. Most athletes use Deca Durabolin for a period of two to four months at a time and often stack it with Methandienone (Dianabol) and Testosterone or even Sustanon. It is ideally stacked with Testosterone enanthate or cypionate because of the length of the esters being similar.

Female athletes may use Deca Durabolin in doses ranging from 50 to 150mg per week. Post cycle therapy with Proviron or Nolvadex is highly recommended to take care of excess estrogen formation and restore the natural production of testosterone, in case it has been suppressed due to prolonged use of Deca Durabolin.

Deca Durabolin Side effects and abuse

Deca Durabolin can lead to inhibition of LH (Luteinizing Hormone) production that stimulates the testes to naturally manufacture testosterone. This anabolic steroid can convert to estrogen via aromatization and some users of Deca Durabolin may experience some heavy nose bleeds with dehydration in rare cases. Abuse or overdosing of this anabolic steroid can lead to health complications like acne/oily skin, insomnia, diarrhea, nausea, testicular atrophy, gynecomastia (including lactation in some cases), and sexual dysfunction.

Deca abuse can lead to other health complications like atrophy of the breasts, early epiphyseal closure, hypercalcemia, hypercalciuria, withdrawal of ovarian action, decreased ejaculatory volume, and more-than-average increase in bone development, suppression of ovarian activity, oedema, and depression.

Abuse of Deca Durabolin can even result in elevated blood pressure, shrinking of the testicles, bone age advancement, bad effect on cholesterol levels, increased aggression, clitoral hypertrophy, infertility, and sexual dysfunction. When abused at extremely high dosages, Deca Durabolin may even cause heart attack, edema, prostate enlargement, menstrual problems, liver toxicity, and liver damage.

The Performance-Enhancing Effects of Deca Durabolin Are Celebrated in Medicine

The scientific community is becoming increasingly excited by the therapeutic use of anabolic steroids for a variety of medical treatments. The same performance-enhancing effects that are demonized in society, and sports in particular, are celebrated for their therapeutic potential. The unfortunate war on anabolic steroids and resulting hysteria have regrettably delayed research into this class of medicines for decades. However, it appears the therapeutic value of anabo steroids can not be overlooked indefinitely as scientific progress marches on in spite of morally-driven obstacles.

Eric Hohmann and colleagues at Central Queensland University experiemented with the use of the anabolic steroid Nandrolone Decanoate after total knee replacement surgery. They summed up the reason that anabolic steroids are a viable and interesting subject for scientific inquiry:

Recently there is an increasing interest in using anabolic steroids for medical conditions such as age related muscle wasting and increase muscle mass in patients with secondary wasting syndromes such as HIV. The main effects are positive anabolic actions on the musculoskeletal system influencing lean body mass, muscle size, strength, protein and bone metabolism and collagen synthesis. The effect is dose dependent and significant increases in strength occur only with doses of 300 mg testosterone or more. Side effects are rare and mostly benign and reversible.

Hohmann’s study involved a small group of elderly individuals undergoing total knee arthroplasty (knee replacement). The treatment protocol involved 50mg of Nandrolone decanoate via intramuscular injection every two weeks for the 6 months; the control group received an equivalent volume injection containing an inert saline solution. Many bodybuilders will be surprised to learn that such low dosages of Deca Durabolin had any effect on strength. There may be several shortcomings to the study design. Nonetheless, the strength gains in the steroid group were significantly greater than those in the control group.

The strength gains didn’t translate directly to an improvement in functional tests. However, research has shown that post-operative strength is a good predictor of long-term prognosis after this type of surgery. The strength gains were retained for 12 months – a full six months after discontinuation of the steroid cycle – and remained significantly better than the control group. The researchers did not observe any side effects from the Nandrolone steroid cycle.

The researchers apparently did not account for any potential suppressive effects of nandrolone decanoate on the functioning of the hypothalamus-pituitary-testicular axis (HPT axis). It is unclear if they measured total testosterone, luteneizing hormone (LH), follicle stimulating hormone (FSH) or any other variables with laboratory blood tests.

According the Michael Scally, M.D., all anabolic steroids, and Nandrolone in particular, are suppressive to the HPT axis. The degree of suppression varies in severity and duration. This causes a resulting condition known as anabolic steroid induced hypogonadism (ASIH) that is marked by a reduction in testosterone naturally produced by the body. ASIH is a side effect that is well-documented and easily treated.

It is possible that results could have been improved with a better steroid cycle design and a post cycle therapy protocol. Scally has described the failure of researchers to address ASIH as one of the major shortcomings of medical research into anabolic steroids.

Methandrostenolone Explained

Perhaps no other anabolic steroid has attained such a degree of notoriety, as has the famed Dianabol. Even today, over 50 years after its introduction to American athletes, and after the immergence of hundreds of other performance enhancing drugs, its use is still as widespread as when it was first released. However, is Dianabol still relevant in today’s modern age of performance enhancement or has it fallen from grace in the face of recent pharmacological advancements?

For those of you who are unaware, Dianabol is what’s known as an oral anabolic steroid. Most commonly, oral steroids are anabolic-androgenic hormones which have been molecularly altered at the 17th carbon position by the attachment of a methyl group, which allows the drug to maintain structural integrity, as it passes through the digestive tract and eventually into the bloodstream. Often, when a steroid is modified through the attachment of a methyl group, its potency is further increased, as is the case with Dianabol.

In short, Dianabol is an excellent size and strength builder. Users can expect wet, but fairly rapid gains in muscle tissue and strength. This is definitely not a steroid one would use if the goal was to look as hard and dry as possible, but when it comes to sheer mass Dianabol is the favorite of many. As a “fast-acting” anabolic steroid, its effects on muscle mass and strength begin to emerge within 1-2 weeks of use and can be rather dramatic at respectable dosages. This makes Dianabol an effective anabolic steroid in a variety of circumstances. In our modern age, this drug is often used to initiate gains at the beginning of a cycle, known as a “kick-start”, or used as a plateau breaker later on in a cycle, when gains have typically begun to stagnate. However, in prior decades Dianabol was used for much longer periods of time by the majority of its users. In any case, Dianabol makes a great choice for those looking for rapid gains in muscle size and strength.

Dianabol undergoes a relatively complex metabolism upon ingestion, leading to the formation of several active & distinct metabolites, most of which are of relevance in determining Dianabol’s overall effect on the body. Therefore, an understanding of and ability to manipulate these metabolites will allow a user to maximize benefits, while minimizing side effects.

Like testosterone, Dianabol does not demonstrate any progestagenic activity, but is easily capable of converting to estrogen through the aromatase enzyme. However, unlike testosterone, Dianabol converts to a more potent form of estrogen, known as methylestradiol. While aromatization to estrogen can result in unwanted side effects, such as water retention, female fat pattern distribution, gynecomastia, and elevated blood pressure, estrogen also results in numerous beneficial and necessary effects on male physiology. Benefits such as an increase in glycogen storage, a positive effect on blood lipids, proper sexual function, and an increase in anabolism are only a few of its positive characteristics, all of which are dependent on optimal levels of systematic estrogen.

The goal of any anabolic steroid user when seeking to build maximum muscle mass and maintain health is not to eliminate estrogen from the system, but to maintain the correct balance between androgens and estrogens. In the case of Dianabol, this goal is met by the use of an ancillary class of drugs, known as aromatase inhibitors. The concurrent use of Dianabol and an “A.I.” will enable users to receive all the benefits this drug has to offer, without experiencing the side effects of excessive estrogen.

Dianabol is also capable of inducing androgenic side effects in its users. In men, these side effects can range from hair-loss, acne, hirsutism, and oily skin, among others. The degree to which these side effects manifest themselves is largely dependent on the dosage employed, as well as on an individual’s genetic propensity to experience a particular side effect. Additionally, being that Dianabol displays a weaker androgen component than testosterone on a mg to mg basis, it is less likely to result in side effects at similar dosages. Personal opinion should dictate to what extent these side effects are acceptable to each user, and dosage should be tailored accordingly.

One of the reasons why Dianabol has become so beloved in the anabolic steroid community is because, quite frankly, users simply feel good when taking it. Dianabol is well-noted to impart an anti-depressant-like effect, and unlike so many other oral anabolic steroid available today, which result in appetite suppression, lethargy, and general malaise, these side effects are almost always non-existent with Dianabol. This makes Dianabol one of the most pleasurable anabolic steroids to utilize on-cycle.

Another standout attribute of Dianabol can be seen in the area of toxicity. While Dianabol is inherently liver-toxic due to methylation, it appears to deliver a reduced toxic-load per effective dose in comparison to many of our other mass-builders, such as Anadrol, SD, and M1T. As a consequence, this drug can be run for longer periods of time without presenting the same degree of risk as the aforementioned drugs. In healthy individuals, this drug can easily be run for 10-12 weeks at moderate dosages before discontinuance should be considered.

While anabolic steroids in general elevate red blood cell count and lead to an improved “pump” during weight training, Dianabol excels in this area. The typical user experience with Dianabol includes extreme muscle pumps in the gym and a perpetual feeling of muscle fullness, even when at rest. Dianabol accomplishes this through multiple pathways, which are comprised of an increase in RBC, an overall increase in blood volume, as well as through significant inhibition of the 11-beta hydroxylase enzyme.

There are some minor disagreements regarding the half-life of Dianabol, with claims ranging anywhere between 3-6 hours. This necessitates a dosing schedule of every 3-6 hours if one desires to maintain even blood levels of the drug throughout the day. The average dosing range for Dianabol is between 20-100 mg daily. Most individuals will use between 30-60 mg per day.

While some users will opt to run this drug alone, best gains will be realized by combining it with an injectable steroid, such as Testosterone. Below, I supply the reader with 2 basic cycle examples using common cycling guidelines. Option №1 is suitable for anyone from beginners to those who prefer keeping dosages on the lower side, while Cycle №2 is more suited to those who have at least a couple cycles under their belt.

Cycle Option №1
Weeks 1-8: Testosterone - 500 mg/week.
Weeks 1-8: Dianabol - 30 mg/day.

Cycle Option №2
Weeks 1-10: Testosterone - 600-800 mg/week.
Weeks 1-9: Nandrolone - 400-600 mg/week.
Weeks 1-10: Dianabol - 50 mg/day.

Despite being birthed in an American lab over a half-century ago, Dianabol is still one of our most effective and well-rounded anabolic steroids, which remains a favorite to this day. It is properly included in the cycles of beginner and advanced athletes alike and at the present time.

Clomid & Post Cycle Recovery

Nearly every bodybuilders is familiar with the name. It is one of the oldest, yet most effective drugs for the treatment of both testosterone and sperm deficiency. In the medical community it has long been established as the gold-standard for inducing ovulation in women and increasing sperm count & motility in men. Bodybuilders typically use the drug for Post cycle therapy a practice engaged in by millions of steroid users world-wide. It would be foolish to discount the role this drug has played in modern steroid culture and even today, it does not appear to be in danger of replacement any time soon.

Also known as Clomiphene Citrate, Clomid is what we call a selective estrogen receptor modulator (S.E.R.M.). Its primary function is to stimulate the testes to produce testosterone and sperm, which it accomplishes through a through a fairly elaborate process. Clomid initiates this process by attaching to estrogen receptor sites in the hypothalamus, preventing circulating estrogen from attaching to these receptor sites. Because these receptors are occupied by Clomid, the hypothalamus is not able to detect the true level of estrogen in the body and therefore, thinks there is an estrogen deficiency. This is called inhibition of the negative feedback loop.

In an effort to increase estrogen levels, the body responds by setting off a cascade of events, ultimately leading to an elevation of testosterone. Why? The male body’s primary means of increasing estrogen is through aromatization, which occurs when testosterone is converted to estrogen via the aromatase enzyme. Therefore, in order to increase estrogen levels, the body must first increase testosterone levels. This is a rather indirect way of solving the problem, but is effective none the less.

After the hypothalamus recognizes the need for additional estrogen, it releases a hormone called GnRH, which orders the pituitary to secrete both LH (leutinizing hormone) and FSH (follicle stimulating hormone). Upon entering the bloodstream, these hormones travel to the testes, signaling them to produce both testosterone and sperm, respectively. This effect will persist for as long as Clomid present and active.

While Clomid can be used for other purposes, this is its main application in the BB’ing community. More specifically, it is typically employed during PCT, in order to help the body restore deficient levels of testosterone and sperm. Oftentimes, BB’rs tend to look at “recovery” as nothing more than the restoration of testosterone levels, but this is far from the truth. In reality, steroids adversely affect multiple bodily systems, all of which should be considered when seeking normalization of the body post-cycle. Two frequently ignored aspects of recovery are the restoration of sperm count & motility. This is especially important for the young, as a properly functioning reproductive system will be appreciated when either the BB’r or his wife decide to start a family.

In comparison to other S.E.R.M.S., such as Nolvadex, Clomid is my preferred choice, due to its more comprehensive nature. It is more effective at increasing sperm count and improving motility (hence, it is the #1 most prescribed fertility treatment in the world), while being equally proficient at elevating testosterone levels. When used for PCT, Clomid is typically administered in a single dose at 50-100 mg per day for a period of 4-6 weeks in length. Some users elect to go up to 150 mg daily, although this is less common. In most cases, Clomid is simply one element in a more thorough post-cycle therapy program, in which both a S.E.R.M. (Clomid) and an anti-estrogen (Aromasin) are combined for superior overall results. Anti-estrogens have also been proven effective for elevating testosterone levels, as documented by multiple clinical studies. When these two drugs are used in concert, a more dramatic effect is achieved.

Some individuals have complained or expressed concern over side effects associated with Clomid use. Some of these potential side effects, such as alterations in visions, are very rare and should not discourage one from using this serm. One doctor, whom I will not name here, has been treating patients with Clomid for 20 years. During that time, he has seen only two individuals complain of vision changes and in both cases the changes were reversed upon cessation of the drug. For further confirmation, a quick search of the BB’ing boards will reveal 100’s, if not 1,000’s of documented experiences, almost all of which are completely devoid of this side effect. Others have noted emotional changes with Clomid, although they are generally transient and mild in nature, if you experience them at all. Many do not. Overall, the drug is well tolerated, with a high rate of user compliance.

There is an ongoing argument as to which S.E.R.M. is best, with some claiming Nolvadex to be superior, while others stand by Clomid as the better drug. Both work remarkably well, prompting some to combine the two for optimal results. This is likely the ideal situation. While they both do essentially the same thing from a recovery perspective, there are positives and negatives associated with each. For example, Nolvadex is stronger per mg, as it results in roughly the same degree of testosterone elevation at 40 mg per day as Clomid does at 150 mg daily. However, I find this argument to be irrelevant, as the total amount of mgs used it not what matters. What is important is how well each drug elevates testosterone when using a maximally effective dose. Let’s compare 2 common aromatase inhibitors in order to make my point. Arimidex is usually dosed at only ½ -2 mg daily, while Aromasin if often dosed at 25-50 mg per day. Does this mean Arimidex is better? Of course, not…it simply means that Arimidex requires a smaller dose in order to elicit a maximum effect. However, when both drugs are administered within their own optimal dosing range, Aromasin produces at least an equal inhibitory response. Besides, the strength of as compound should not be your sole consideration, as Aromasin has additional benefits not found with Arimidex, such as the inability to cause estrogen rebound and being more forgiving on the lipids. One must evaluate the full range of effects with each drug before making a determination of superiority.

Along those same lines, Clomid possesses some benefits Nolvadex does not. In the medical community, Clomid is the first line of defense in the fight for female and male fertility all over the world. The reason for this is simple…it simply works better in this regard. With the health of the reproductive system being a primary concern during PCT (or at least it should be), this benefit has significant value. This makes Clomid the more comprehensive recovery drug. On the flip-side, Nolvadex has a positive effect on cholesterol values, which can be helpful for those who struggle in this area, but it also reduces circulating levels of IGF-1; a key hormone involved in the muscle building process. I could continue, but you get the point. When evaluating the full range of effects for each drug, in my opinion, Clomid takes the cake as the S.E.R.M of choice. Now, not everyone feels the same way I do, so you may want to conduct your own research in the search for answers.
Still, I believe this entire versus debate is not one we should invest much time on, as our primary focus should be on getting the best results possible. Towards this end, the concomitant administration of both drugs has proven superior to using either one alone. However, if I were going to choose just one, you know what my choice would be. 

Oral Activation Of Steroids

The subject of anabolic steroids, and the different ways that have been found to make them orally active, has been tossed around lately on the internet mags. This is an interesting topic to the science minded out there, but beyond that, it also has potential utility to the prohormone supplements. The following is my take on the subject, including scientific references and conjecture on my part.

Testosterone is the primary androgen in the human, and is the golden standard by which all other steroids are compared. Unfortunately, testosterone has very poor activity when taken orally. This necessitates that testosterone be administered by extra-oral means such by injection, subcutaneous pellet implant, and transdermal gel or patch.

Scientists have developed several synthetic testosterone derivatives that have increased oral bioavailability. The first synthetic alteration that scientists utilized is known as 17 alpha alkylation. 17a alkylation involves the addition of an alkyl group (methyl or ethyl) to the alpha position of the 17 carbon of the steroid backbone. The alkylation at this position prevents the major route of androgen deactivaton – oxidation to a 17-keto steroid - from taking place. This allows a large part of the steroid to avoid liver first pass metabolic degradation. Examples of 17a alkylated steroids are methyltestosterone. While 17a alkylation is a very effective means of rendering steroids orally active, it suffers from a serious drawback. These steroids are all to some extent toxic to the liver. Some are more toxic than others, but they all have been associated with this problem. Jaundice is not completely uncommon with the usage of this stuff, although this condition is generally confined to individuals who are predisposed to liver problems. Several cases of liver cancer have supposedly been linked to 17a alkylated steroids, however, nothing definitive has been established in this regard. On the other hand, it is somewhat common to observe increases in blood test indicators of liver stress such as BSP retention, and intrahepatic cholestasis (a condition where bile clogs up and stops flowing from the liver). While the dangers of 17a alkylated steroids are not trivial, they still comprise some of the most potent anabolic agents available, and therefore their use continues. Most smart bodybuilders are aware of the potential toxicities of these steroids, and therefore they are judicious with their use of them.

After ingestion, most steroids make their way to the intestines where they are absorbed into the portal circulation. The portal circulation carries the steroid directly to the liver, which is the workhouse of destructive metabolism and inactivation of drugs. As a result, if the steroid is not protected in some way, very little will make it through the liver and into the rest of the body where it can do its magic.

In addition to the portal route, there is another route through which substances can be absorbed into the body from the intestine. If a substance is lipophilic (fat like) enough it will be absorbed in the same manner that dietary fat is. Dietary fat is incorporated into chylomicra, which are small fat globules composed of protein and fat. These chylomicra are absorbed into the lymphatic circulation, which by passes the liver. If you make a steroid lipophilic enough by altering its structure, then it too will incorporate into chylomicra and absorb into the lymphatic system. Once in the lymphatic system it can cross over into the general blood circulation, making it there without being subjected to the massive metabolic breakdown in the liver.

Scientists have found that by adding lipophilic side chains to steroids, they will to some extent be absorbed into the lymphatic system. If the side chain is linked on in such a way that it can hydrolyze (break apart) easily after being absorbed, the steroid is essentially rendered orally active. Two side chains that have been utilized to increase the oral bioavailability of steroids through increased hepatic absorption are long chain alkyl ester groups, such as is seen with testosterone undecanoate (andriol), and enyl ether groups, such as is seen with quinbolone (anabolicum vaster).

The term “orally active” is of course a relative term. Lipophilically modified steroids are more orally active than the free parent steroids, however, they are nowhere near as active as the 17alpha-alkylated steroids. Testosterone undecanoate is probably the most commonly known lipophilically modified androgen, and it is not considered a very potent compound (its recommended daily dosage is about 240mg). In fact, one study found the oral administration of testosterone undecanoate led only to an absolute testosterone bioavailability of 6.83 +/- 3.32%. That is very slight, especially considering the fact that in the same study they found the bioavailability of straight testosterone to be 3.56 +/- 2.45% . That means Testosterone undecanoate is just a little less than twice as orally active as free testosterone, which is unimpressive to say the least.

The other problem with lipophilic steroid preparations is the high variability in absorption from one person to another. In other words, one guy might absorb the stuff very well while the other guy might absorb very little. There is also high variation within individuals themselves, depending on their gastrointestinal condition when they take the stuff. In another study, ten post-menopausal women were given 40 mg of TU and their peak blood values were recorded. The values varied widely - more than ten fold (range: 5.8-64.0 nmol/L) - amongst the subjects.

There is no specific data I can find on the bioavailabilty of enyl ether compounds, but since their mode of action is identical to long chain alkyl ester compounds like Testosterone undecanoate, it is a fair assumption that they too are not outstandingly high in oral bioavailability, or in consistency of absorption. What I do know is that the one and only enyl ether oral steroid on the market today (quinbolone) is generally regarded by European bodybuilders / athletes as too weak to even bother taking.

What is Primobolan?

Primobolan - is a common name of the drug called Methenolone Enanthate. This steroid is by its nature more anabolic than androgenic. Androgenic ratio is only 6% and anabolic ratio is 68%. Primo comes in oral and injectable forms, however, injectable is more effective because it is not being destroyed by liver..

Primobolan is an unique steroid, with the properties which do not have any other drug. Primo does not cause estrogen-related side effects, which is a significant advantage over other steroids. This means that acne, edema, and other negative effects will not be a problem. Thus, Primobolan is a very attractive in comparison with other steroids, especially for those, who are prone to various estrogen-related side effects. Because of the low water retention, Primobolan is often more effective than other drugs for quality mass building. It is not only effective, due to lower levels of water retention, but it is very useful because of its anabolic nature, which has a positive effect on the development of muscles.

The only problem which Primobolan possesses is slow muscle growth and, therefore, the cycle should be more than 8 weeks, preferably 12 weeks. Because of the absence of edema, muscle growth, which will be noticeable when using primo, will actually increase the quality mass and not water retention in the body. When using primobolan, muscle build-up is better preserved, though not so rapidly increasing, as with other drugs. But make no mistake – though Primobolan does not have such side effects as other drugs – Post Cycle Therapy (PCT) is still necessary, use Nolvadex or Clomid.

Cycles and information on the usage

As stated above, Primobolan is high quality steroid. Dosages below 400 mg / week is a waste of money because injectable primo contains enanthate. “The more is better” is not true for all steroids due to side effects, however, this is true for primo. The best dosage will be primo 400-800 mg/week in combination with testosterone. Primobolan provides two main effects in this case. First, this is enhanced muscle growth, therefore, 500mg primo /week in combo with test equals to the effect of 750 mg primo / week. Secondly, Primo + diet+ hard training provides wonderful results and qualitative muscle growth.

For those who want to use Primobolan without testosterone it is necessary to use a minimum of 600-800 mg per week. If you will be able to afford 1000 mg per week, the reward will be enormous. Some people tend to use it with Trenbolone and this is quite possible. But without testosterone, you may need to use sex-enchancing drugs for potency. The most efficient way of training – is the one that includes Primobolan, Testosterone and Trenbolone Acetate. Another recommended cycle is Primobolan (600-1000mg per week) and Anavar (Oxandrolone) (60-80mg daily).

Because of enanthate nature, the cycle should last at least 8 weeks but better do it 12 weeks or more. Furthermore, Primobolan lifetime is 5-6 weeks, so the actual cycle length becomes even more. Primobolan does not cause loss of appetite. Unlike other drugs it can be used for up to 20 weeks.

Testosterone Injections works wonders for males with this deficiency

Testosterone injections are one of the treatment options that helps restore the normal levels of testosterone in individuals with this deficiency. You might wonder why there is a need to maintain the normal levels of testosterone in blood.

Testosterone is a hormone essential for the vitality of the body. It helps you stay young and in shape apart from that, it has various other functions that contribute to the overall well being of a male’s health. Just like other hormones, testosterone is produced from a gland and the amounts of its secretions are affected by a number of factors. In any case, the variation from the normal testosterone levels can have drastic effects on your body. Luckily, testosterone injections can bring testosterone levels back to normal.

Many people don’t feel the need to get a treatment for this deficiency. It’s a sheer lack of awareness. If you know that declining testosterone can actually lead to cardiovascular diseases or cause osteoporosis in some cases. Seriously, you will have an increased risk of heart diseases. Testosterone injections, on the other hand, maintain the level of testosterone in blood and reduce the risk of contracting such diseases.

For getting a shot of testosterone, the individual needs to stick to a proper procedure. In fact, if you are deficient in testosterone, you will have to go through a series of tests, first to find whether or not you lack this hormone and second to determine if you go through temporary fluctuations. Basically, the test determines the amount of available testosterone in your body. The ideal time for test is early morning because that’s the time when testosterone levels will be at their peak. After doing the tests, the amounts or dose of testosterone injections is determined.

Among the different products on testosterone therapy, their injections are the most effective means to bring your testosterone levels in the normal range. Mainly, there are two types of testosterone injections that can restore the normal levels of the hormone in your blood. However, for both males and women, separate types of injections are used.
In males, testosterone injections are administered when the ability of the body to produce this hormone is ether temporarily or permanently hampered. Usually, the male injections have a dosage of 20-30 mg that has to be given after every 2-3 weeks on average. However, this is an approximate amount that tends to vary according to the age of the male. At puberty, for instance, the level of testosterone is at its peak which starts to decline after the age of 30. When a man has crossed his 50, he will certainly have reduced testosterone levels.

The second types of injections are those used by women. Hence the testosterone injections for women are standardized on different concentration than the one used by males. The reason is that testosterone is a male hormone and it is produced in women in lesser quantities. The most appropriate means of giving testosterone injection in women is via intramuscular channel.

Injectable testosterone is available in various forms. The same drug can have different names in different countries or due to change in company. You won’t find it to be a very long list but it covers all major forms of testosterone injections. The formulations of testosterone esters are prepared in cottonseed or sesame seed oil.

Weight loss and Fat loss with Clenbuterol

Clenbuterol is a drug which is generally taken for losing extra weight. This drug is being used for weight loss for years. Clenbuterol (clen) is being used worldwide for fat loss. A huge number of people are using Clen that do not have time to go to gym or do not want to make a huge change in their diet.

Actions in the body

However, though this drug is being used for the same weight loss effect; there are some basic differences in the way of taking them and their action in human body. Clenbuterol isdesigned to be used for bronchial asthma. But it can be used to lose weight faster than any other weight loss medicine. It works through protein degradation in muscle cells. It has a fast action in the metabolism of the body. Rarely do any other drugs have the same capability to do so fast.

Recommendation

Clenbuterol have specific ways of working within the human body. So, you need to have a clear idea of it’s actions before taking this drug. It’s always best to consult your doctor before starting taking any of the fat burning drugs to avoid the side effects of the drugs. As with other drugs, this drug have some side effects too.

Now, coming to Clenbuterol, it has a different taking dose for the women and men. Generally women are recommended to take up to 120 mcg per day and men are recommended to take up to 140 mcg per day. In no way is this meant as a cycle protocal. The numbers that are mentioned are on the high end of any Clen cycle. It’s always wise to start very low on the doage and work your way up. The higher dosage can cause your body to tremble. You may feel like jumping out of your own skin. So start low.

Equipoise by Geneza Pharmaceuticals for Safer Muscle Development

Equipoise (Boldenone Undecylenate) is a testosterone derivative wherein a double bond was added between the 1 and 2 carbons of the naturally-occurring hormone. Designed as a longer-lasting injectable alternative to the widely popular orally-administered Dbol (Dianabol), Eq shares the strong anabolic effects of testosterone but is much less androgenic. Equipoise is a decent steroid that is quite popular for bodybuilders.

Because of the double bond, boldenone offers unique characteristics that are not found in Equipoise steroids bottleother steroids. For one, it resists conversion by the 5-alpha-reductase enzyme, but the small quantities that is nonetheless converted produces a very potent derivative, dihydroboldenone, which is roughly 7 times as anabolic as testosterone. The effect of boldanone is not mediated by dihydroboldenone, though, which led to the conclusion that it works by upgrading the androgen receptor thereby allowing the hormones to exert a greater anabolic effect, as proven in the case of strong androgenic drugs like anadrol.

The appetite-enhancing property of Eq is also well-known among users. This increase in appetite aids the muscle-building process, as high nutritional intake hastens protein synthesis that is known to be the primary cause of muscle mass buildup - as more protein molecules are made available to the muscular system, the faster the body heals torn muscle fibers. Equipoise also increases nitrogen retention in the muscles, which further aids protein synthesis.

Another unique property of boldanone is its very slow rate of aromatization (conversion to estrogen), which goes as slow as half of the rate for testosterone. This results in very insignificant estrogenic side effects to users, even in fairly high doses and in longer periods. Thus, this is a safe alternative to testosterone, as estrogenice side effects such as oily skin, acne, and gynecomastia for men and development of male sexual characteristics in women are rarely reported. The low androgenic effect is the reason why many male and female bodybuilders and athletes prefer to use this compound, alone or stacked with other drugs.

Many steroids cause increases in the red blood cells (RBCs) but Equipoise does it better than most (with the exception of erythropoietin or EPO, which is precisely designed to raise erythrocytes). More RBCs equate to more oxygen in the blood, which in turn increases stamina that translates to better speed, endurance and strength. Also, better glycogenolysis (repletion of glycogen lost during exercise) is observed during use of Eq.

The slow but constant muscle buildup one gets from Equipoise is due to the undeclynate ester that is used, which, with 11 carbons, is longer than the decanoate ester used in Deca. Thus, the effect of the drug is felt for a longer time than ordinary testosterone (it stays active for more than four weeks). For this reason, use of the drug by tested athletes is not advised, as it is detectable in doping tests for a long time. Still, with so many benefits one gets from using Equipoise, the limited side effects, including its low toxicity on the liver, and high availability, countless enthusiasts, male or female, favor it over other steroids.

Users usually stack boldenone with testosterone ester like enanthate or cypionate for good gains in a bulking cycle. For those who favor Deca, adding a little boldenone will improve appetite and vascularity. For cutting cycles, stacking Eq with trenbolone, stanazol or testosterone propionate would give muscle hardness and strength, and increase muscle definition. The use of ancillary drugs such as anti-aromatases or anti-estrogens is seldom required when using boldenone.

Anadrol by Geneza Pharmaceuticals

Anadrol is an effective steroid which gives fabulous gains in strength and size. This steroid has been in circulation since 1960 and is taken orally. Bodybuilders and power lifters buy Anadrol as it gives dramatic gains.

This steroid exhibits high anabolic and androgenic properties and does not bind strongly to the androgen receptors. It has a half cycle of only 16 hours and is taken several times during the day.

If you are looking for remarkable gains in weight and size and that too in a short span of time then you should definitely buy Anadrol. This steroid is perfect for bulking cycles as the user can gain an increase in weight up to thirty pounds in a few weeks only by taking this steroid daily.

Much of the weight gain produced in users who buy Anadrol is due to water accumulation. Water retention is quite prominent with this drug. In this condition, water collects under the skin. Water retention adds weight to the body and causes the muscles to bloat up. However water retention caused by Anadrol has one advantage; water retention lubricates the joints and protects them when lifting heavy loads.

Another reason bodybuilders and power lifters buy Anadrol is that it stimulates the process of protein synthesis in the body which is the prime force behind the impressive build up of muscle mass. It not only has dramatic muscle building abilities but also effectively inhibits protein catabolism which causes the muscles to be wasted.

Sportsperson also buy Anadrol because it raises the endurance level in the body; giving more stamina for rigorous workouts. It also helps the body to recover rapidly from the exhausting exercises. In short it enhances the performance level of the user.

The recommended dose of Anadrol is 50 to 150 mg per day which should be divided into many smaller doses. Women are advised not to take more than 25 mg per day otherwise Virilization can occur.

Surprisingly Anadrol has many uses in the field of medicine. It increases the red blood cell count in the body and is used to treat anemia. It is highly effective in combating muscle wasting diseases such as AIDS and can be used to cure osteoporosis as well. It makes the immune system of the body stronger.

Medical uses of anabolic steroids

Most of us think that anabolic steroids are just used by strong-built bodybuilders and athletes but you would be amazed to know that steroids have been, still being used, and will be used in the world of medication.

In the world of medicines, anabolic steroids have endless benefits. They are used to treat severe health complications when other treatment options fail to deliver any results. Some of the ailments for which steroids are used these days are severe asthma and Crohn’s disease; steroids are also used for treating health complications such as breast cancer, prostate cancer, airway inflammation, Alzheimer’s disease, flu, and Kawasaki’s disease.

Apart from all these uses, steroids are also used to treat sexual disorders such as ovulation, infertility, low sperm count, and sexual dysfunction besides treating males with testicular cancer by promoting testosterone after testes removal.

It is imperative to note that only a registered medical practitioner is qualified enough to prescribe anabolic steroids for medical purposes and self-prescription can prove fatal. In the absence of qualified knowledge or steroid abuse, side effects such as acne, insomnia, depression, breast development in men, and menstrual irregularities in women can happen and thus self-prescribed use of steroids must be best avoided.

In short, anabolic steroids are life-saving drugs that are primarily meant for legitimate purposes such as research and medications. Their unique properties and benefits make them first and obvious choice of medical practitioners and general physicians all over the world and for genuine reasons.

Anabolic steroids and training

Anabolics play an effective role in enhancing and increasing the performance of the athletes and other sports persons both men and women. However, the main reason to worry is the occurrence of many kinds of side effects related to the health of all people who use anabolic steroids for their increased and enhanced performance. Anabolic steroids have plenty of effects on the organ systems and plenty of side effects on the body of the person. Generally, the anabolics, which is orally administered, can have more adverse effects than the ones that are being parenterally administered. These steroids have positive effects as well but normally their negative ones are more dangerous and care should be taken while taking them to avoid or reduce the negative effects of them.

When talking about anabolic diet training, you must have in mind that it allows only a few grams of carbohydrates a day to body fat reduction whereas the need is to have a higher number of grams of carbohydrates for the typical adult healthy person. The main idea behind this purpose is to lose the fat of the body without having any effect on the muscle mass and that is the thing, which body builders and weight lifters normally like to do. However, they must take a balanced diet to avoid any kind of adverse effects on their body and to minimize them at least. The main purpose of diet training is to change the fuel source for the body and use all the energy from the fat instead of burning lots of energy from the carbohydrates. The recommended foods that you can use in your diet training include the fish, chicken, cheese, vegetables and a few others. These diets must be taken during the days of high proteins and fats. The persons using this strategy should eat small meals many times a day and must consume their body weight in calories to a high amount.

For cutting, muscle hardness and density can be greatly improved when combining Boldenone Undeclylenat with a non-aromatizable steroid such as Trenbolone Acetate  or Methenolone Enanthate (Primobolan Depot,Primobol). Long esters Testosterones (Testosteron Depot) are used in diet anabolic steroid cycles with Human Growth Hormone like Norditropin or Genotropin.

Training for Strength

The person who wants to get through the adverse effects of anabolics must focus on building muscle, but at the same time, fats must be reduced or lose. Some exercises like multiple joint exercises must be done to simulate the hormones and muscle mass related to the anabolics. Best time for strength training is afternoon or early in the morning because of these times body will burn fat more than at the other times. The basic thing that must be kept in mind is that at each point you do strength training, you must make it hard, heavy and it must make all your body work perfectly to reduce the bad effects.

For quality and strength you can add 25 mg + Oxandrolone/day with Deca-Durabolin or Boldenone Undeclylenat.

Training of Cardiovascular System

Cardiovascular training has its importance in the same way as the importance of the strength and diet training. Normally, cardiovascular training is advisable for few days normally for a week in which long cardio walk is included for almost an hour. You can do the treadmill or outdoor trainings on the non-strength days, and on high intensity days, you must keep your routine. However, it is important to practice high intensity intervals to get more out of your training, especially the cardiovascular one. These trainings can really keep you away from the hazardous and adverse effects of anabolics in many ways.

The Bicep Exercise That Strengthens Your Grip

Lift more weight in every exercise with this simple tweak to the standard curl

You train your legs, arms, abs, glutes, and just about every other major muscle group in your body. But if you neglect your mitts, you could be holding yourself back in the weight room. “Grip strength is essential to lifting power and stamina,” says James Sjostrom. “If you can’t grip it, you can’t lift it.” That’s why Sjostrom recommends adding the dumbbell hammer curl to your exercise arsenal. Instead of your palms facing forward like they do with a standard dumbbell curl, your palms face each other. “This simple tweak doesn’t allow the weight to rest in your palms, so your fingers have to work overtime to keep the weight in your hand every rep,” he says. It’ll bump up your biceps while taxing your grip, for a one-two punch that’ll help you lift more weight in every exercise.

Ready to try it?

The Benefits Of HGH

Human growth hormone is also called HGH or rHGH. This is created by the pituitary gland. Its primary form is composed of a 191 amino acid chain. In our youth, rHGH or somatotropin, has a major role in the development of muscles, tissues and bone. A lack of this hormone can lead to growth defects like dwarfism and too much of it can cause deformities like giantism or abnormal growth patterns.

In adults, HGH is needed to keep our muscular tissue from wasting away. It also regulates metabolism, keeps our immune system healthy and maintains the stability of other tissues. However, as we age, the decreased levels of HGH production can lead to various health conditions, primarily, muscle wastage. Humans that are 30 and older may produce as little as 20% of the amount of HGH that they used to. Thus, one will have less strength and stamina.

Luckily, scientific research has paid off and a synthetic version is available to the general public. Somatropin is a performance and physical enhancement aid that is manufactured from somatotropin, which is the natural growth hormone. Somatropin is an exact copy of our normal HGH.

Bodybuilders and athletes in training will benefit from the use of HGH, as it aids in the development of muscle cells, which was once predetermined by genetics. Keep in mind that after puberty, there is a significant decline in hormone secretion. Thus, muscular development ceases and a person has to forcibly increase the size of the muscular tissue with the help of weights.

People using HGH can expect to develop more muscular cells and tissue. Thus, it is more popular, especially with people who are genetically predisposed to being lanky. Aside from that, a person who uses HGH can expect an increase in energy and stamina.

As one gets older, weight management becomes a problem. This is because of the decrease in HGH production, which plays a large part in metabolism. It also explains why it was easier to lose weight before we were 30. Thus, supplementing growth hormones can help you burn fat, especially since it boosts energy levels as well. HGH secretion leads to IGF-1 secretion. IGF-1 makes our body use up our fat stores before our food. Therefore, it targets our lipids or fat cells and makes us lose weight.

HGH remains superior to steroids because it also hastens recovery after a workout. Weight training enthusiasts and scientists swear by this because it helps strengthen joints and ligaments as well. If you are someone who is committed to getting a better physique, this is a product you should consider.

Sagging skin is caused by a decline in HGH production as well. Thus, people who are 30 and older may begin to notice mild to severe areas of sagging, especially after losing weight. While cocoa butter, hyaluronic acid and other creams may offer temporary firmness, taking HGH supplements will help your skin restore its optimal suppleness. Therefore, it is a must for people who work out to lose weight or tone their physiques.

Studies show that HGH supplementation can positively affect one’s blood sugar levels. Since it improves blood circulation and fights fat, this hormone is useful in treating type 2 diabetes. It helps reduce the dependence of people with type 2 diabetes to insulin injections.